As trade was an important source of wealth for the Baiyue peoples of coastal southern China, the region south of the Yangtze River attracted the attention of Emperor Qin Shi Huang, and he undertook a series of military campaigns to conquer it. Lured by its temperate climate, fertile fields, maritime trade routes, relative security from warring factions to the west and northwest, and access to luxury tropical products from Southeast Asia, the emperor sent armies to conquer the Yue kingdoms in 221 BC. Military expeditions against the region were dispatched between 221 and 214 BC. It would take five successive military excursions before the Qin finally defeated the Yue in 214 BC.

The Han campaigns against Minyue were a series of three Han military campaigns dispatched against the Minyue state. The first campaign was in response to Minyue's invasion of Eastern Ou in 138 BC. In 135 BC, a second campaign was sent to intervene in a war between Minyue and Nanyue. After the campaign, Minyue was partitioned into Minyue, ruled by a Han proxy king named Zou Yushan, and Dongyue. During the concluding months of 111 BC, after the unsuccessful uprising led by Zou Yushan in thwarting General Yang Pu's conspiratorial intentions to undermine him, the aspiration for autonomous rule in Dongyue gradually waned. The rebellion instigated by Zou was suppressed, prompting the Han dynasty's complete annexation of Dongyue into its dominion and the conquest of the residual territories that constituted the former Minyue, effectively consolidating the permanent integration of both domains into the Han empire indefinitely.