Rabbit, Run is a 1960 novel by John Updike. The novel depicts three months in the life of a 26-year-old former high school basketball player named Harry "Rabbit" Angstrom, who is trapped in a loveless marriage and a boring sales job, and attempts to escape the constraints of his life. It spawned several sequels, including Rabbit Redux, Rabbit is Rich and Rabbit at Rest, as well as a related 2001 novella, Rabbit Remembered. In these novels, Updike takes a comical and retrospective look at the relentless questing life of Rabbit against the background of the major events of the latter half of the 20th century.

John Hoyer Updike was an American novelist, poet, short-story writer, art critic, and literary critic. One of only four writers to win the Pulitzer Prize for Fiction more than once, Updike published more than twenty novels, more than a dozen short-story collections, as well as poetry, art and literary criticism and children's books during his career.