The raid on Glenn Springs occurred on the night of May 5–6, 1916, when Mexican Villistas and Carrancistas attacked the towns of Boquillas and Glenn Springs, Texas. In Glenn Springs, the raiders burned several buildings and fought a three-hour battle with a small force of American soldiers who were stationed there. At the same time, a second party of rebels robbed a general store and a silver mine in Boquillas. Four Americans were killed and the rebels took two hostages to Coahuila. In response to the attack, the United States Army launched a short punitive expedition into Mexico, fought with the rebels, and rescued the captives.

The Pancho Villa Expedition—now known officially in the United States as the Mexican Expedition, but originally referred to as the "Punitive Expedition, U.S. Army"—was a military operation conducted by the United States Army against the paramilitary forces of Mexican revolutionary Francisco "Pancho" Villa from March 14, 1916, to February 7, 1917, during the Mexican Revolution of 1910–1920.