Rassenschande or Blutschande was an anti-miscegenation concept in Nazi German racial policy, pertaining to sexual relations between Aryans and non-Aryans. It was put into practice by policies like the Aryan certificate requirement, and later by anti-miscegenation laws such as the Nuremberg Laws, adopted unanimously by the Reichstag on 15 September 1935. Initially, these laws referred predominantly to relations between ethnic Germans and non-Aryans, regardless of citizenship. In the early stages the culprits were targeted informally; later, they were punished systematically and legally.

Miscegenation is marriage or admixture between people who are members of different races. The word, now usually considered pejorative, is derived from a combination of the Latin terms miscere and genus. The word first appeared in Miscegenation: The Theory of the Blending of the Races, Applied to the American White Man and Negro, a hoax anti-abolitionist pamphlet David Goodman Croly and others published anonymously in advance of the 1864 presidential election in the United States. The term came to be associated with laws that banned interracial marriage and sex, which were known as anti-miscegenation laws. These laws were overruled federally in 1967, and by the year 2000, all states including Alabama had removed them from their laws. In the 21st century, newer scientific data shows that human populations are actually genetically quite similar. Studies show that races are more of an arbitrary social construct, and do not actually have a major genetic delineation.