Ripley is a town in southeastern Payne County, Oklahoma, United States. The population was 423 at the 2010 census, a decline of 9.2 percent from the figure of 444 in 2000. The town was named after Edward Ripley, the 14th president of the Atchison, Topeka and Santa Fe Railway.

Payne County is located in the U.S. state of Oklahoma. As of the 2020 census, its population was 81,646. Its county seat is Stillwater. The county was created in 1890 as part of Oklahoma Territory and is named for Capt. David L. Payne, a leader of the "Boomers".