Heinrich Hermann Robert Koch was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he is regarded as one of the main founders of modern bacteriology. As such he is popularly nicknamed the father of microbiology, and as the father of medical bacteriology. His discovery of the anthrax bacterium in 1876 is considered as the birth of modern bacteriology. Koch used his discoveries to establish that germs "could cause a specific disease" and directly provided proofs for the germ theory of diseases, therefore creating the scientific basis of public health, saving millions of lives. For his life's work Koch is seen as one of the founders of modern medicine.
The Anthrax Disease Cycle. Anthrax particles live in a vegetative state until exposed to oxygen, where they form many infectious spores. They can live in the soil and be consumed by herbivores. Large herbivores, like cows, are most susceptible to anthrax disease, and humans are affected by animal waste, fecal or corpses, by these herbivores. Anthrax infection is spread to humans when spores gain entry into the body, whether that is from inhalation, open wounds, or another method of entrance. Once inside, the spores are activated, allowing the bacteria to multiply and spread their toxins. Another spread of infection is through biting flies, like mosquitoes, that come in contact with the blood and feces of herbivores, preceded by contact with human flesh (information from Bergman
Koch's drawing of tuberculosis bacilli in 1882 (from Die Ätiologie der Tuberkulose)
Photograph of Koch (third from the right) and other members of the German Cholera Commission in Egypt, 1884
An agar plate is a Petri dish that contains a growth medium solidified with agar, used to culture microorganisms. Sometimes selective compounds are added to influence growth, such as antibiotics.
Contamination on an agar plate
96 pinner used to perform spot assays with yeast, fungal or bacterial cells
An agar plate being viewed in an electronic colony counter
Red blood cells on an agar plate are used to diagnose infection. On the left is a positive Staphylococcus infection, on the right a positive Streptococcus culture.