Sainte-Madeleine is a village municipality in southwestern Quebec, Canada in Les Maskoutains Regional County Municipality. The population as of the Canada 2011 Census was 2,356.

Autoroute 20 is a Quebec Autoroute, following the Saint Lawrence River through one of the more densely populated parts of Canada, with its central section forming the main route of the Trans-Canada Highway from the A-25 interchange to the A-85 interchange. At 585 km (363.5 mi), it is the longest Autoroute in Quebec. It is one of two main links between Montreal and Quebec City; the other is the A-40.