Saltsburg is a borough in Indiana County, Pennsylvania, United States. Its location is in Western Pennsylvania, in the southwestern corner of Indiana County near its border with Westmoreland County.

Indiana County is a county in the Commonwealth of Pennsylvania. It is located in the west central part of Pennsylvania. As of the 2020 census, the population was 83,246. Its county seat is Indiana. Indiana County comprises the Indiana, PA Micropolitan Statistical Area, which is also included in the Pittsburgh-New Castle-Weirton, PA-WV-OH Combined Statistical Area. The county is part of the Southwest Pennsylvania region of the state.