Samlesbury Hall is a historic house in Samlesbury, Lancashire, England, six miles (10 km) east of Preston. It was built in 1325 by Gilbert de Southworth, and was the primary home of the Southworth family until the early 17th century.

Samlesbury is a village and civil parish in South Ribble, Lancashire, England. Samlesbury Hall, a historic house, is in the village, as is Samlesbury Aerodrome and a large modern brewery owned by Anheuser-Busch InBev. The population at the 2011 census was 1,206.