Samuel Griffin was a lawyer, soldier and politician from Virginia. Following his service during the American Revolutionary War as a Continental Army officer, Griffin served as mayor of Williamsburg, Virginia, as well as represented the former state capitol in the Virginia House of Delegates, then in the U.S. House of Representatives.

The Battle of Iron Works Hill, also known as the Battle of Mount Holly, was a series of minor skirmishes that took place on December 22 and 23, 1776, during the American Revolutionary War. The fighting took place in Mount Holly, New Jersey, between an American force mostly composed of colonial militia under Colonel Samuel Griffin and a force of 2,000 Hessians and British regulars under Carl von Donop.