San Cristóbal Hill is a hill in northern Santiago, Chile. It rises 850 m AMSL and about 300 m above the rest of Santiago; the peak is the third highest point in the city, after Cerro Manquehue and Cerro Renca. Cerro San Cristóbal was named by the Spanish conquistadors for St Christopher, in recognition of its use as a landmark. Its original indigenous name is Tupahue.

Santiago, also known as Santiago de Chile, is the capital and largest city of Chile and one of the largest cities in the Americas. It is located in the country's central valley and is the center of the Santiago Metropolitan Region, which has a population of seven million, representing 40% of Chile's total population. Most of the city is situated between 500–650 m (1,640–2,133 ft) above sea level.