Santa Fe County is located in the U.S. state of New Mexico. As of the 2020 census, the population was 154,823, making it New Mexico's third-most populous county, after Bernalillo County and Doña Ana County. Its county seat is Santa Fe, the state capital.

Bernalillo County is the most populous county in the U.S. state of New Mexico. As of the 2020 census, the population was 676,444. The county seat, Albuquerque, is the most populous city in New Mexico.