Santa Maria del Carmine is a church of the Carmelite Order, in the Oltrarno district of Florence, in Tuscany, Italy. It is famous as the location of the Brancacci Chapel housing outstanding Renaissance frescoes by Masaccio and Masolino da Panicale, later finished by Filippino Lippi.

The Brancacci Chapel is a chapel in the Church of Santa Maria del Carmine in Florence, central Italy. It is sometimes called the "Sistine Chapel of the early Renaissance" for its painting cycle, among the most famous and influential of the period. Construction of the chapel was commissioned by Felice Brancacci and begun in 1422. The paintings were executed over the years 1425 to 1427. Public access is currently gained via the neighbouring convent, designed by Brunelleschi. The church and the chapel are treated as separate places to visit and as such have different opening times and it is quite difficult to see the rest of the church from the chapel.