The Scroll and Key Society is a secret society, founded in 1842 at Yale University, in New Haven, Connecticut. It is one of the oldest Yale secret societies and reputedly the wealthiest. The society is one of the reputed "Big Three" societies at Yale, along with Skull and Bones and Wolf's Head. Each spring the society admits fifteen rising seniors to participate in its activities and carry on its traditions.

There are many collegiate secret societies in North America. They vary greatly in their level of secrecy and the degree of independence from their universities. A collegiate secret society makes a significant effort to keep affairs, membership rolls, signs of recognition, initiation, or other aspects secret from the public.