The Second Italo-Senussi War, also referred to as the Pacification of Libya, was a conflict that occurred during the Italian colonization of Libya between Italian military forces and indigenous rebels associated with the Senussi Order. The war lasted from 1923 until 1932, when the principal Senussi leader, Omar al-Mukhtar, was captured and executed. The Libyan genocide took place during and after the conflict.

The Italian colonization of Libya began in 1911 and it lasted until 1943. The country, which was previously an Ottoman possession, was occupied by Italy in 1911 after the Italo-Turkish War, which resulted in the establishment of two colonies: Italian Tripolitania and Italian Cyrenaica. In 1934, the two colonies were merged into one colony which was named the colony of Italian Libya. In 1937, this colony was divided into four provinces, and in 1939, the coastal provinces became a part of metropolitan Italy. The colonization lasted until Libya's occupation by Allied forces in 1943, but it was not until the 1947 Paris Peace Treaty that Italy officially renounced all of its claims to Libya's territory.