The Secretariat of State is the oldest dicastery in the Roman Curia, the central papal governing bureaucracy of the Catholic Church. It is headed by the Cardinal Secretary of State and performs all the political and diplomatic functions of the Holy See. The Secretariat is divided into three sections: the Section for General Affairs, the Section for Relations with States, and, since 2017, the Section for Diplomatic Staff.

The Roman Curia comprises the administrative institutions of the Holy See and the central body through which the affairs of the Roman Catholic Church are conducted. The Roman Curia is the institution which the Roman Pontiff ordinarily makes use of in the exercise of his supreme pastoral office and universal mission in the world. It is at the service of the Pope, successor of Peter, and of the Bishops, successors of the Apostles, according to the modalities that are proper to the nature of each one, fulfilling their function with an evangelical spirit, working for the good and at the service of communion, unity and edification of the Universal Church and attending to the demands of the world in which the Church is called to fulfill its mission.