Seleucus VI Epiphanes Nicator was a Hellenistic Seleucid monarch who ruled Syria between 96 and 94 BC. He was the son of Antiochus VIII and his Ptolemaic Egyptian wife Tryphaena. Seleucus VI lived during a period of civil war between his father and his uncle Antiochus IX, which ended in 96 BC when Antiochus VIII was assassinated. Antiochus IX then occupied the capital Antioch while Seleucus VI established his power-base in western Cilicia and himself prepared for war. In 95 BC, Antiochus IX marched against his nephew, but lost the battle and was killed. Seleucus VI became the master of the capital but had to share Syria with his brother Demetrius III, based in Damascus, and his cousin, Antiochus IX's son Antiochus X.

Antiochus VIII Epiphanes/Callinicus/Philometor, nicknamed Grypus, was the ruler of the Hellenistic Seleucid Empire from 125 to 96 BC. He was the younger son of Demetrius II and Cleopatra Thea. He may have spent his early life in Athens and returned to Syria after the deaths of his father and brother Seleucus V. At first he was joint ruler with his mother. Fearing her influence, Antiochus VIII had Cleopatra Thea poisoned in 121 BC.