Senators for life in Italy are members of the Italian Senate who are either appointed, limited in number up to five, by the Italian president "for outstanding patriotic merits in the social, scientific, artistic or literary field" or are former presidents and thus senators for life ex officio.

The Senate of the Republic, or simply the Senate, is the upper house of the bicameral Italian Parliament, the lower house being the Chamber of Deputies. The two houses together form a perfect bicameral system, meaning they perform identical functions, but do so separately. Pursuant to the Articles 57, 58, and 59 of the Italian Constitution, the Senate has 200 elective members, of which 196 are elected from Italian constituencies, and 4 from Italian citizens living abroad. Furthermore, there is a small number of senators for life, either appointed or ex officio. It was established in its current form on 8 May 1948, but previously existed during the Kingdom of Italy as Senato del Regno, itself a continuation of the Senato Subalpino of Sardinia established on 8 May 1848. Members of the Senate are styled Senator or The Honourable Senator and they meet at Palazzo Madama, Rome.