The siege of Caffa was a 14th-century military encounter when Jani Beg of the Golden Horde besieged the city of Caffa, between two periods in the 1340s. The city of Caffa, a Genoese colony, was a vita
The remains of a Genoese fortress in Feodosia
The Black Death was a plague pandemic that occurred in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history, leading to the death of up to 50 million people, around 30% to
Siege of Caffa
…were forced to withdraw. The siege is famous for a story recounted by Italian notary Gabriel de Mussis, which attributed the subsequent spread of the Black Death to plague-infested corpses having been launched over the walls at the end of the siege. Caffa (modern-day Feodosia) was a thriving port city on the…
Yersinia pestis (200 × magnification), the bacterium that causes plague
The Oriental rat flea (Xenopsylla cheopis) engorged with blood. This species of flea is the primary vector for the transmission of Yersinia pestis, the organism responsible for spreading bubonic plague in most plague epidemics. Both male and female fleas feed on blood and can transmit the infection.
Oriental rat flea (Xenopsylla cheopis) infected with the Yersinia pestis bacterium which appears as a dark mass in the gut. The foregut (proventriculus) of this flea is blocked by a Y. pestis biofilm; when the flea feeds on an uninfected host Y. pestis is regurgitated into the wound, causing infection.
Skeletons in a mass grave from 1720 to 1721 in Martigues, near Marseille in southern France, yielded molecular evidence of the orientalis strain of Yersinia pestis, the organism responsible for bubonic plague. The second pandemic of bubonic plague was active in Europe from 1347, the beginning of the Black Death, until 1750.