Sikka is a regency within East Nusa Tenggara province, Indonesia, on the island of Flores. It is bordered to the west by Ende Regency and to the east by East Flores Regency. It covers an area of 1,675.36 km2 and had a population of 300,301 at the 2010 census and 321,953 at the 2020 Census; the official estimate as at mid 2023 was 335,360 - comprising 163,060 males and 172,300 females). The capital is the town of Maumere, which comprises the districts of Alok Barat, Alok and Alok Timur.

Flores is one of the Lesser Sunda Islands, a group of islands in the eastern half of Indonesia. Administratively, it forms the largest island in the East Nusa Tenggara Province. Including Komodo and Rinca islands off its west coast, the land area is 14,731.67 km2, and the population was 1,878,875 in the 2020 Census ; the official estimate as of mid-2023 was 1,962,405. The largest towns are Maumere and Ende. The name Flores is of Portuguese origin, meaning "Flowers".