The Sisters of the Holy Family of Nazareth are a Roman Catholic religious institute that was founded in Rome in 1875 by Blessed Mary Mother of Jesus the Good Shepherd. The Sisters of the Holy Family are an apostolic, international congregation, located on four continents and in thirteen countries. There are five provinces in the United States. A Sister of this congregation is identified by the initials CSFN placed after her name.

The Holy Family consists of the Child Jesus, the Virgin Mary and Saint Joseph. The subject became popular in art from the 1490s on, but veneration of the Holy Family was formally begun in the 17th century by Saint François de Laval, the first bishop of New France, who founded a confraternity.