The Smithsonian Institution, or simply the Smithsonian, is a group of museums, education and research centers, the largest such complex in the world, created by the U.S. government "for the increase and diffusion of knowledge." Founded on August 10, 1846, it operates as a trust instrumentality and is not formally a part of any of the three branches of the federal government. The institution is named after its founding donor, British scientist James Smithson. It was originally organized as the United States National Museum, but that name ceased to exist administratively in 1967.

The Pacific Railroad Surveys (1853–1855) were a series of explorations of the American West designed to find and document possible routes for a transcontinental railroad across North America. The expeditions included surveyors, scientists, and artists and resulted in an immense body of data covering at least 400,000 square miles (1,000,000 km2) on the American West. "These volumes... constitute probably the most important single contemporary source of knowledge on Western geography and history and their value is greatly enhanced by the inclusion of many beautiful plates in color of scenery, native inhabitants, fauna and flora of the Western country." Published by the United States War Department from 1855 to 1860, the surveys contained significant material on natural history, including many illustrations of reptiles, amphibians, birds, and mammals. In addition to describing the route, these surveys also reported on the geology, zoology, botany, paleontology of the land as well as provided ethnographic descriptions of the Native peoples encountered during the surveys.