Southwest Florida International Airport is a major county-owned airport in the South Fort Myers area of unincorporated Lee County, Florida, United States. The airport serves the Southwest Florida region, including the Cape Coral-Fort Myers, Naples-Marco Island, and Punta Gorda metropolitan areas, and is a U.S. Customs and Border Protection port of entry. It currently is the second-busiest single-runway airport in the United States, after San Diego International Airport. In 2022, the airport served 10,343,802 passengers, the most in its history.

Lee County is located in southwestern Florida, United States, on the Gulf Coast. As of the 2020 census, its population was 760,822. In 2022, the population was 822,453, making it the eighth-most populous county in the state. The county seat is Fort Myers, with a population of 86,395 as of the 2020 census, and the largest city is Cape Coral, with an estimated 2020 population of 194,016.