A spacecraft is a vehicle that is designed to fly in outer space and operate there. Spacecraft are used for a variety of purposes, including communications, Earth observation, meteorology, navigation, space colonization, planetary exploration, and transportation of humans and cargo. All spacecraft except single-stage-to-orbit vehicles cannot get into space on their own, and require a launch vehicle.

An orbital spaceflight is a spaceflight in which a spacecraft is placed on a trajectory where it could remain in space for at least one orbit. To do this around the Earth, it must be on a free trajectory which has an altitude at perigee around 80 kilometers (50 mi); this is the boundary of space as defined by NASA, the US Air Force and the FAA. To remain in orbit at this altitude requires an orbital speed of ~7.8 km/s. Orbital speed is slower for higher orbits, but attaining them requires greater delta-v. The Fédération Aéronautique Internationale has established the Kármán line at an altitude of 100 km (62 mi) as a working definition for the boundary between aeronautics and astronautics. This is used because at an altitude of about 100 km (62 mi), as Theodore von Kármán calculated, a vehicle would have to travel faster than orbital velocity to derive sufficient aerodynamic lift from the atmosphere to support itself.