Reina Sofía (F84) is the fourth of six Spanish-built Santa María-class frigates of the Spanish Navy. The Santa María class is based on the American Oliver Hazard Perry-class design, providing an anti-air warfare platform with anti-submarine and anti-surface warfare capabilities at a reduced cost. Reina Sofía was constructed by Bazan and was laid down on 12 October 1987 and launched on 19 July 1989. The ship was commissioned in 1990 and has seen service in the Mediterranean Sea and off Somalia.

The Santa María class of guided missile frigates is the Spanish Navy's designation for six warships based on the United States Oliver Hazard Perry-class frigates. Spanish ships have a slightly bigger beam and were built with a greater weight reserve for future improvements. Other changes from the basic model include Meroka replacing Phalanx and a RAN-12L air search radar to provide low horizon coverage against sea skimmers cueing the Meroka CIWS mount. The Nettunel EW suite replaced the SLQ-32 system fitted aboard US ships. The first ship Santa Maria entered service in 1986.