The Spen Valley Line was a railway that connected Mirfield with Low Moor through the Spen Valley in West Yorkshire, England. Opened up by the Lancashire and Yorkshire Railway in 1847, with full opening to Low Moor in 1848, the line served a busy industrial and textile area and allowed a connection for trains between Huddersfield and Bradford. The line was absorbed by the London & North Western Railway, the London Midland and Scottish Railway (LMS) and British Railways on Nationalisation. A separate link between Heckmondwike Central and Thornhill that opened later and was known as the Ravensthorpe Branch, allowed through running to Wakefield and beyond. The line was closed down to passengers in 1965 with freight continuing sporadically until 1981. A Spur onto the former Leeds New Line from the Ravensthorpe Branch kept the very southern end open until the late 1980s. The majority of the route is now the Spen Valley Greenway cycle path.

Mirfield railway station serves the town of Mirfield in West Yorkshire, England. It lies on the Huddersfield Line and is managed by both Northern and Grand Central train operating companies, and is served by TransPennine Express as well. The station is 4 miles (6 km) north east from Huddersfield.