Speyer, historically known in English as Spires, is a city in Rhineland-Palatinate in Germany with approximately 50,000 inhabitants. Located on the left bank of the river Rhine, Speyer lies 25 km south of Ludwigshafen and Mannheim, and 21 km south-west of Heidelberg. Founded by the Romans, it is one of Germany's oldest cities. Speyer Cathedral, a number of other churches, and the Altpörtel dominate the Speyer landscape. In the cathedral, beneath the high altar, are the tombs of eight Holy Roman Emperors and German kings.

The history of the Jews in Germany goes back at least to the year 321 CE, and continued through the Early Middle Ages and High Middle Ages when Jewish immigrants founded the Ashkenazi Jewish community. The community survived under Charlemagne, but suffered during the Crusades. Accusations of well poisoning during the Black Death (1346–53) led to mass slaughter of German Jews, while others fled in large numbers to Poland. The Jewish communities of the cities of Mainz, Speyer and Worms became the center of Jewish life during medieval times. "This was a golden age as area bishops protected the Jews, resulting in increased trade and prosperity."