St. Anthony Hall or the Fraternity of Delta Psi is an American fraternity and literary society. Its first chapter was founded at Columbia University on January 17, 1847, the feast day of Saint Anthony the Great. The fraternity is a non–religious, nonsectarian organization. In 1879, William Raimond Baird's American College Fraternities characterized the fraternity as having "the reputation of being the most secret of all the college societies." A 2015 writer for Vanity Fair says the fraternity is "a cross between Skull and Bones and a Princeton eating club, with a large heaping of Society and more than a dash of Animal House." Nearly all chapters of St. Anthony Hall are coed.

Columbia University, officially Columbia University in the City of New York, is a private, Ivy League, research university in New York City, United States. Established in 1754 as King's College on the grounds of Trinity Church in Manhattan, it is the oldest institution of higher education in New York and the fifth-oldest in the United States and is considered one of the most prestigious universities in the world.