The Star-Club was a music club in Hamburg, Germany, that opened on Friday 13 April 1962, and was initially operated by Manfred Weissleder and Horst Fascher. In the 1960s, many of the giants of rock music played at the club. The club closed on 31 December 1969 and the building it occupied was destroyed by a fire in 1987. The address of the club was Große Freiheit 39 in the St. Pauli quarter of Hamburg. Große Freiheit is a side street of the Reeperbahn. The club had a capacity of 2,000 people, and cinema-style seating.

St. Pauli is a quarter of the city of Hamburg belonging to the centrally located Hamburg-Mitte borough. Situated on the right bank of the Elbe river, the nearby Landungsbrücken is a northern part of the port of Hamburg. St. Pauli contains a world-famous red-light district around the iconic Reeperbahn area. As of 2020 the area had 21,902 residents.