The Stone Arch Bridge is a former railroad bridge crossing the Mississippi River at Saint Anthony Falls in downtown Minneapolis, Minnesota. It is the only arched bridge made of stone on the entire Mississippi River. It is the second oldest bridge on the river next to Eads Bridge. The bridge was built to connect the railway system to the new Union Depot, which at that time was planned to be built between Hennepin Avenue and Nicollet Avenue. The bridge was completed in 1883, costing $650,000 at the time. 117 Portland Avenue is the general address of the historic complex.

Saint Anthony Falls, or the Falls of Saint Anthony, located at the northeastern edge of downtown Minneapolis, Minnesota, is the only natural major waterfall on the Mississippi River. Throughout the mid-to-late 1800s, various dams were built atop the east and west faces of the falls to support the milling industry that spurred the growth of the city of Minneapolis. In 1880, the central face of the falls was reinforced with a sloping timber apron to stop the upstream erosion of the falls. In the 1950s, the apron was rebuilt with concrete, which makes up the most visible portion of the falls today. A series of locks were constructed in the 1950s and 1960s to extend navigation to points upstream.