Stress in the aviation industry is a common phenomenon composed of three sources: physiological stressors, psychological stressors, and environmental stressors. Professional pilots can experience stress in flight, on the ground during work-related activities, and during personal time because of the influence of their occupation. An airline pilot can be an extremely stressful job due to the workload, responsibilities and safety of the thousands of passengers they transport around the world. Chronic levels of stress can negatively impact one's health, job performance and cognitive functioning. Being exposed to stress does not always negatively influence humans because it can motivate people to improve and help them adapt to a new environment. Unfortunate accidents start to occur when a pilot is under excessive stress, as it dramatically affects his or her physical, emotional, and mental conditions. Stress "jeopardizes decision-making relevance and cognitive functioning" and it is a prominent cause of pilot error. Being a pilot is considered a unique job that requires managing high workloads and good psychological and physical health. Unlike the other professional jobs, pilots are considered to be highly affected by stress levels. One study states that 70% of surgeons agreed that stress and fatigue don't impact their performance level, while only 26% of pilots denied that stress influences their performance. Pilots themselves realize how powerful stress can be, and yet many accidents and incidents continues to occur and have occurred, such as Asiana Airlines Flight 214, American Airlines Flight 1420, and Polish Air Force Tu-154.

On 10 April 2010, a Tupolev Tu-154 aircraft operating Polish Air Force Flight 101 crashed near the Russian city of Smolensk, killing all 96 people on board. Among the victims were the president of Poland, Lech Kaczyński, and his wife, Maria; the former president of Poland in exile, Ryszard Kaczorowski; the chief of the Polish General Staff and other senior Polish military officers; the president of the National Bank of Poland; Polish government officials; 18 members of the Polish parliament; senior members of the Polish clergy; and relatives of victims of the Katyn massacre. The group was arriving from Warsaw to attend an event commemorating the 70th anniversary of the massacre, which took place not far from Smolensk.