Summation (neurophysiology)
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Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and i
Basic ways that neurons can interact with each other when converting input to output
A diagram of temporal summation
Depolarization
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In biology, depolarization or hypopolarization is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell com
Summation (neurophysiology)
…under one of two categories, depending on the ion channels gated or modulated by the neurotransmitter receptor. Excitatory neurotransmitters produce depolarization of the postsynaptic cell, whereas the hyperpolarization produced by an inhibitory neurotransmitter will mitigate the effects of an excitatory…
Action potential in a neuron, showing depolarization, in which the cell's internal charge becomes less negative (more positive), and repolarization, where the internal charge returns to a more negative value.
Voltage-gated sodium channel. Open channel (top) carries an influx of Na+ ions, giving rise to depolarization. As the channel becomes closed/inactivated (bottom), the depolarization ends.
Structure of a neuron
Summation of stimuli at an axon hillock