Susanna Hall was the oldest child of William Shakespeare and Anne Hathaway and the older sister of twins Judith and Hamnet Shakespeare. Susanna married John Hall, a local physician, in 1607. They had one daughter, Elizabeth, in 1608. Elizabeth married Thomas Nash, son of Anthony Nash on 22 April 1626 at Holy Trinity Church, Stratford-upon-Avon.

Elizabeth, Lady Bernard was the granddaughter of the English poet, playwright and actor William Shakespeare. Despite two marriages, she had no children, and was his last surviving descendant.