Swinburne Island is a 4-acre (1.6 ha) artificial island in Lower New York Bay, east of Staten Island in New York City. It was used for quarantine of immigrants. Swinburne Island is the smaller of two nearby islands, the other being Hoffman Island to the north.

Lower New York Bay is a section of New York Bay south of the Narrows. The eastern end of the Bay is marked by two spits of land, Sandy Hook, New Jersey, and Rockaway, Queens. The waterway between the spits connects the Bay to the Atlantic Ocean at the New York Bight. Traversing the floor of the Bay southeasterly from the Narrows to the Bight and beyond is Hudson Canyon.