The Syracuse Orange men's lacrosse team represents Syracuse University in NCAA Division I men's college lacrosse. The Orange have won 15 national championship titles and currently compete as a member of the Atlantic Coast Conference men's lacrosse conference. Syracuse plays its home games at the JMA Wireless Dome in Syracuse, New York.

College lacrosse is played by student-athletes at colleges and universities in the United States and Canada. In both countries, men's field lacrosse and women's lacrosse are played at both the varsity and club levels. College lacrosse in Canada is sponsored by the Canadian University Field Lacrosse Association (CUFLA) and Maritime University Field Lacrosse League (MUFLL), while in the United States, varsity men's and women's lacrosse is governed by the National Collegiate Athletic Association (NCAA), National Junior College Athletic Association (NJCAA) and National Association of Intercollegiate Athletics (NAIA). There are also university lacrosse programs in the United Kingdom sponsored by British Universities and Colleges Sport (BUCS) and programs in Japan.