The Tarantula Nebula is a large H II region in the Large Magellanic Cloud (LMC), forming its south-east corner.

An H II region or HII region is a region of interstellar atomic hydrogen that is ionized. It is typically in a molecular cloud of partially ionized gas in which star formation has recently taken place, with a size ranging from one to hundreds of light years, and density from a few to about a million particles per cubic centimetre. The Orion Nebula, now known to be an H II region, was observed in 1610 by Nicolas-Claude Fabri de Peiresc by telescope, the first such object discovered.