The Tenerife airport disaster occurred on 27 March 1977, when two Boeing 747 passenger jets collided on the runway at Los Rodeos Airport on the Spanish island of Tenerife. The collision occurred when KLM Flight 4805 initiated its takeoff run during dense fog while Pan Am Flight 1736 was still on the runway. The impact and resulting fire killed all on board KLM Flight 4805 and most of the occupants of Pan Am Flight 1736, with only 61 survivors in the front section of the aircraft. With a total of 583 fatalities, the disaster is the deadliest accident in aviation history.

The Boeing 747 is a long-range wide-body airliner designed and manufactured by Boeing Commercial Airplanes in the United States between 1968 and 2023. After introducing the 707 in October 1958, Pan Am wanted a jet 2+1⁄2 times its size, to reduce its seat cost by 30%. In 1965, Joe Sutter left the 737 development program to design the 747. In April 1966, Pan Am ordered 25 Boeing 747-100 aircraft, and in late 1966, Pratt & Whitney agreed to develop the JT9D engine, a high-bypass turbofan. On September 30, 1968, the first 747 was rolled out of the custom-built Everett Plant, the world's largest building by volume. The 747's first flight took place on February 9, 1969, and the 747 was certified in December of that year. It entered service with Pan Am on January 22, 1970. The 747 was the first airplane called a "Jumbo Jet" as the first wide-body airliner.