The Best of Talking Heads is a greatest hits album by American rock band Talking Heads, released on August 17, 2004 by Sire, Warner Bros. Records, and Rhino Entertainment.

Once in a Lifetime is a three-CD box set by American post-punk/new wave band Talking Heads, released in the United States by Sire, Warner Bros, and Rhino in 2003. The set also includes a DVD containing an expanded version of the music video compilation Storytelling Giant. The discs are packaged in a wide horizontal book that recalls a CD longbox, featuring paintings by Russian artists Vladimir Dubossarsky and Alexander Vinogradov and with art direction by Stefan Sagmeister. Sagmeister would later work with David Byrne and Brian Eno on their 2008 collaborative album Everything That Happens Will Happen Today.