The Boston Associates were a loosely linked group of investors in 19th-century New England. They included Nathan Appleton, Patrick Tracy Jackson, Abbott Lawrence, and Amos Lawrence. Often related directly or through marriage, they were based in Boston, Massachusetts. The term "Boston Associates" was coined by historian and professor of economics and Marxism, Vera Shlakman in her 1935 work, Economic History of a Factory Town, A Study of Chicopee, Massachusetts.

The Boston Manufacturing Company was a business that operated one of the first factories in America. It was organized in 1813 by Francis Cabot Lowell, a wealthy Boston merchant, in partnership with a group of investors later known as The Boston Associates, for the manufacture of cotton textiles. It built the first integrated spinning and weaving factory in the world at Waltham, Massachusetts, using water power. They used plans for a power loom that he smuggled out of England as well as trade secrets from the earlier horse-powered Beverly Cotton Manufactory, of Beverly, Massachusetts, of 1788. This was the largest factory in the U.S., with a workforce of about 300. It was a very efficient, highly profitable mill that, with the aid of the Tariff of 1816, competed effectively with British textiles at a time when many smaller operations were being forced out of business. While the Rhode Island System that followed was famously employed by Samuel Slater, the Boston Associates improved upon it with the "Waltham System". The idea was successfully copied at Lowell, Massachusetts, and elsewhere in New England. Many rural towns now had their own textile mills.