The Hitch-Hiker is a 1953 American independent film noir thriller co-written and directed by Ida Lupino, and starring Edmond O'Brien, William Talman and Frank Lovejoy. Based on the 1950 killing spree of Billy Cook, the film follows two friends who are taken hostage by a murderous hitchhiker during an automobile trip to Mexico.

Ida Lupino was a British actress, director, writer, and producer. Throughout her 48-year career, she appeared in 59 films and directed eight, working primarily in the United States, where she became a citizen in 1948. She is widely regarded as the most prominent female filmmaker working in the 1950s during the Hollywood studio system. With her independent production company, she co-wrote and co-produced several social-message films and became the first woman to direct a film noir, The Hitch-Hiker, in 1953.