The Holocaust in the Independent State of Croatia involved the genocide of Jews, Serbs and Romani within the Independent State of Croatia, a fascist puppet state that existed during World War II, led by the Ustaše regime, which ruled an occupied area of Yugoslavia including most of the territory of modern-day Croatia, the whole of modern-day Bosnia and Herzegovina and the eastern part of Syrmia (Serbia). Of the 39,000 Jews who lived in the NDH in 1941, the United States Holocaust Memorial Museum states that more than 30,000 were murdered. Of these, 6,200 were shipped to Nazi Germany and the rest of them were murdered in the NDH, the vast majority in Ustaše-run concentration camps, such as Jasenovac. The Ustaše were the only quisling forces in Yugoslavia who operated their own extermination camps for the purpose of murdering Jews and members of other ethnic groups.

The Genocide of Serbs in the Independent State of Croatia was the systematic persecution of Serbs committed during World War II by the fascist Ustaše regime in the Nazi German puppet state known as the Independent State of Croatia between 1941 and 1945. It was carried out through executions in death camps, as well as through mass murder, ethnic cleansing, deportations, forced conversions, and war rape. This genocide was simultaneously carried out with the Holocaust in the NDH as well as the genocide of Roma, by combining Nazi racial policies with the ultimate goal of creating an ethnically pure Greater Croatia.