The Immaculate Collection is the first greatest hits album by American singer Madonna, released on November 13, 1990, by Sire Records. It contains fifteen of her hit singles recorded throughout the 1980s, as well as two brand new tracks, "Justify My Love" and "Rescue Me". All the previously released material were reworked through the QSound audio technology, becoming the first ever album to use it. Meanwhile, the new material saw Madonna working with Lenny Kravitz and Shep Pettibone. The album's title is a pun on the Immaculate Conception, a Marian dogma of the Catholic Church.

A greatest hits album or best-of album is a type of compilation album that collects popular and commercially successful songs by a particular artist or band. While greatest hits albums are typically supported by the artist, they can also be created by record companies without express approval from the original artist as a means to generate sales. They are typically regarded as a good starting point for new fans of an artist, but are sometimes criticized by longtime fans as not inclusive enough or necessary at all.