"The Vampyre" is a short work of prose fiction written in 1819 by John William Polidori taken from the story Lord Byron told as part of a contest among Polidori, Mary Shelley, Lord Byron, and Percy Shelley. The same contest produced the novel Frankenstein; or, The Modern Prometheus. "The Vampyre" is often viewed as the progenitor of the romantic vampire genre of fantasy fiction. The work is described by Christopher Frayling as "the first story successfully to fuse the disparate elements of vampirism into a coherent literary genre."

John William Polidori was a British writer and physician. He is known for his associations with the Romantic movement and credited by some as the creator of the vampire genre of fantasy fiction. His most successful work was the short story "The Vampyre" (1819), the first published modern vampire story. Although the story was at first erroneously credited to Lord Byron, both Byron and Polidori affirmed that the author was Polidori.