The fourth season of the television series The Wire commenced airing in the United States on September 10, 2006, concluded on December 10, 2006, and contained 13 episodes. It introduces Baltimore's school system and several middle school students while continuing to examine the remnants of the Barksdale Organization, the ascendant Stanfield Organization, the Baltimore Police Department and politicians.

The Wire is an American crime drama television series created and primarily written by American author and former police reporter David Simon. The series was broadcast by the cable network HBO in the United States. The Wire premiered on June 2, 2002, and ended on March 9, 2008, comprising 60 episodes over five seasons. The idea for the show started out as a police drama loosely based on the experiences of Simon's writing partner Ed Burns, a former homicide detective and public school teacher.