Theodore Dwight Weld was one of the architects of the American abolitionist movement during its formative years from 1830 to 1844, playing a role as writer, editor, speaker, and organizer. He is best known for his co-authorship of the authoritative compendium American Slavery as It Is: Testimony of a Thousand Witnesses, published in 1839. Harriet Beecher Stowe partly based Uncle Tom’s Cabin on Weld's text; the latter is regarded as second only to the former in its influence on the antislavery movement. Weld remained dedicated to the abolitionist movement until slavery was ended by the Thirteenth Amendment to the United States Constitution in 1865.

In the United States, abolitionism, the movement that sought to end slavery in the country, was active from the colonial era until the American Civil War, the end of which brought about the abolition of American slavery, except as punishment for a crime, through the Thirteenth Amendment to the United States Constitution.