Thesprotia is one of the regional units of Greece. It is part of the Epirus region. Its capital and largest town is Igoumenitsa. Thesprotia is named after the Thesprotians, an ancient Greek tribe that inhabited the region in antiquity.

Epirus is a traditional geographic and modern administrative region in northwestern Greece. It borders the regions of Western Macedonia and Thessaly to the east, West Greece to the south, the Ionian Sea and Ionian Islands to the west and Albania to the north. The region has an area of about 9,200 km2 (3,600 sq mi). It is part of the wider historical region of Epirus, which overlaps modern Albania and Greece but lies mostly within Greek territory.