Tiberius Claudius Pompeianus was a politician and military commander during the 2nd century in the Roman Empire. A general under Emperor Marcus Aurelius, Pompeianus distinguished himself during Rome's wars against the Parthians and the Marcomanni. He was a member of the imperial family due to his marriage to Lucilla, a daughter of Marcus Aurelius, and was a key figure during the emperor's reign. Pompeianus was offered the imperial throne three times, though he refused to claim the title for himself.

Roman Syria was an early Roman province annexed to the Roman Republic in 64 BC by Pompey in the Third Mithridatic War following the defeat of King of Armenia Tigranes the Great, who had become the protector of the Hellenistic kingdom of Syria.