Tiye was the Great Royal Wife of the Egyptian pharaoh Amenhotep III, mother of pharaoh Akhenaten and grandmother of pharaoh Tutankhamun; her parents were Yuya and Thuya. In 2010, DNA analysis confirmed her as the mummy known as "The Elder Lady" found in the tomb of Amenhotep II (KV35) in 1898.

Great Royal Wife, or alternatively, Chief King's Wife, is the title that was used to refer to the principal wife of the pharaoh of Ancient Egypt, who served many official functions.