Total depravity is a Protestant theological doctrine derived from the concept of original sin. It teaches that, as a consequence of the Fall, every person born into the world is enslaved to the service of sin as a result of their fallen nature and, apart from the efficacious (irresistible) or prevenient (enabling) grace of God, is completely unable to choose by themselves to follow God, refrain from evil, or accept the gift of salvation as it is offered.
A Sistine Chapel fresco depicts the expulsion of Adam and Eve from the garden of Eden for their sin of eating from the fruit of the Tree of the knowledge of good and evil.
Original sin is the Christian doctrine that holds that humans, through the fact of birth, inherit a tainted nature with a proclivity to sinful conduct in need of regeneration. The biblical basis for the belief is generally found in Genesis 3, in a line in Psalm 51:5, and in Paul's Epistle to the Romans, 5:12-21.
Depiction of the sin of Adam and Eve (The Garden of Eden with the Fall of Man by Jan Brueghel the Elder and Pieter Paul Rubens)
Michelangelo's painting of the sin of Adam and Eve from the Sistine Chapel ceiling
The Fall of Adam and Eve, by Antonio Rizzo, 1476
Augustine of Hippo wrote that original sin is transmitted by concupiscence and enfeebles freedom of the will without destroying it.