Travis Thompson Tygart is an American lawyer and CEO of the United States Anti-Doping Agency (USADA). He is best known for his role in exposing Lance Armstrong's massive doping operation.

United States Anti-Doping Agency v. Lance Armstrong, the Lance Armstrong doping case, was a major doping investigation that led to retired American road racing cyclist Lance Armstrong being stripped of his seven consecutive Tour de France titles, along with one Olympic medal, and his eventual admission to using performance-enhancing drugs. The United States Anti-Doping Agency (USADA) portrayed Armstrong as the ringleader of what it called "the most sophisticated, professionalized and successful doping program that sport has ever seen."